AGRIPA.ORG

Covadonga Alonso Marti

Investigadora del Departamento de Biotecnología (INIA)

Basic info

Name: Covadonga Alonso Marti

About me: Investigadora del Departamento de Biotecnología (INIA)

Líneas de Investigación
  • Interacción Virus-Célula. Proteómica y Transcriptómica
  • Virus de la Peste porcina africana
  • Estrategias de intervención frente a enfermedades víricas
  • Biotecnología
  • Biología Molecular y Celular
  • Patogenesis viral
Actividades

  • ICTV Presidenta del Grupo de Estudio Asfarviridae del Comité Internacional de Taxonomía de virus (ICTV) desde 2015
  • Chief Executive Global African Swine Fever Research Alliance (GARA) http://www.ars.usda.gov/GARA/ 
  • Junta Directiva de la Sociedad Española de Virología, Vicesecretaria.  http://sevirologia.es/
  • Experta Invitada de la FAO en el African swine fever Prevention and Control Forum organizado por FAO y el Ministerio de Agricultura de China. 2015.
  • Miembro del Comité organizador del XIII Congreso Nacional de Virología, Madrid 2015 www.congresonacionalvirología2015.com
  • MASTER UNIVERSITARIO EN VIROLOGIA,  Universidad Complutense de Madrid. Coordinadora de la asignatura Interacción Virus-Célula y del Trabajo Fin de Máster http://www.ucm.es/mastervirologiaucm/
  • Editor invitado. Special Issue African swine fever. Virus Research Volume 173, Issue 1, 2013 Special Issue African Swine Fever 
Publicaciones recientes

Borca M.V., V. O’Donnell, L.G. Holinka,  D.K. Rai, B. Stanford, M. Alfano, J. Carlson, P.A. Azzinaro, C. Alonso, D.P. Gladue. 2016. Identification of a BAT3 as an essential host factor for African Swine Fever Virus protein EP152R. Virus Research Sept;223:181-189

Muñoz-Moreno R., M.A. Cuesta-Geijo, C. Martínez-Romero, L. Barrado-Gil, I. Galindo, A. García-Sastre and C. Alonso. 2016. Antiviral role of Interferon-induced Transmembrane proteins in African swine fever virus infection PLoS ONE 11(4): e0154366. doi:10.1371/journal.pone.0154366. 

 

Klionsky D.J.,...C. Alonso…et al. 2016. Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy, 2nd Edition. Autophagy 12 (1), 1-222, 2016. IF 11,753

 

Cuesta-Geijo M.A., M. Chiappi, I. Galindo, L. Barrado-Gil,  R. Muñoz-Moreno, José L. Carrascosa and C. Alonso. 2016. Cholesterol flux is required for endosomal progression of African swine fever virus. Journal of Virology 90 (3): 1534-43. doi: 10.1128/JVI.02694-15. CLAVE:A IF: 4.439  PMID: 26608317

Metz, G.E., I. Galindo, M.M. Abeyá, M.G. Echeverría and C. Alonso. 2016. Intrinsic, Extrinsic and Endoplasmic Reticulum stress-induced apoptosis in RK13 cells infected with Equine Arteritis Virus. Virus Research 213: 219-223. DOI: 10.1016/j.virusres.2015.12.010 CLAVE:R  IF: 2.941 PMID: 26732484

 

Muñoz-Moreno R., I. Galindo, M.A. Cuesta-Geijo, L. Barrado-Gil and C. Alonso. 2015. Host cell targets for African swine fever virus. Special issue Cell Response to Viral Infection. Virus Research, 209: 118-127. doi:10.1016/j.virusres.2015.05.026. CLAVE:R  IF: 2.941 PMID: 26057710

 

Muñoz-Moreno R., L. Barrado-Gil, I. Galindo and C. Alonso. 2015 Analysis of HDAC6 and BAG3-aggresome pathways in African swine fever viral factory formation. Viruses 7, 1823-1831 doi: 10.3390/v7041823 CLAVE:A  IF: 3.279 PMID: 25856634

 

Galindo I., M.A. Cuesta-Geijo, K. Hlavova, R. Muñoz-Moreno, Lucía Barrado-Gil, Javier Dominguez and C. Alonso. 2015. African swine fever virus infects macrophages, the natural host cells, via clathrin- and cholesterol-dependent endocytosis. Virus Research, 200: 45-55. DOI: 10.1016/j.virusres.2015.01.022. CLAVE:A  IF: 2.941 PMID: 25662020

C. Alonso. African swine fever conquers new territories.Virus Research 2013 173: 1-2. CLAVE:A IF: 2.941PMID: 23376880

C. Alonso, I. Galindo, M.A. Cuesta-Geijo, M. Cabezas, B. Hernáez, R. Muñoz-Moreno. AfricanSwineFever Virus-CellInteractions: From Virus Entry to Cell Survival.Virus Research 2013 173: 42-57. PMID:23262167

Escribano J.M., I. Galindo, C. Alonso. Antibody-mediated neutralization of African swine fever virus. Myths and facts.Virus Research 2013 173: 101-109. CLAVE:A IF: 2.941 PMID: 23159730

Cuesta-Geijo M.A., I. Galindo, B. Hernáez, J.I. Quetglás, I. Dalmau-Mena and C. Alonso. Endosomal maturation, Rab7 GTPase and Phosphoinositides in African Swine Fever Virus entry. PLoSONE 2012, 7: e48853 IF: 4.4PMID:23133661

Galindo I., B. Hernáez, M.A. Cuesta-Geijo, I. Dalmau-Mena and C. Alonso. The ATF6 branch of Unfolded Protein Response and Apoptosis are activated to promote African Swine Fever virus infection. Cell Death and Disease 2012 Jul 5;3:e341. CLAVE:A IF: 6.044 (35/184 Cell Biology)PMID: 22764100

Moros M., B. Hernáez, E. Garet, J. T. Dias, B. Sáez, V. Grazu, A. González- Fernández, C. Alonso, J.M. De La Fuente. MonosaccharidesVersus PEG-Functionalized NPs: Influence in the Cellular Uptake. ACS Nano 2012. 6(2):1565-77. CLAVE:A IF: 9.865PMID: 22214244

Quetglas J.I., Hernaez B., I. Galindo, R. Muñoz-Moreno, M.A.Cuesta-Geijo and C. Alonso Small Rho GTPases and cholesterol biosynthetic pathway intermediates in African swine fever virus infection. Journal of Virology2012 Feb;86(3):1758-67 CLAVE:A IF: 5.2PMID: 22114329

Galindo I., B. Hernáez, J. Berná, J. Fenoll, J.L. Cenis, J.M. Escribano and C. Alonso.Comparative inhibitory activity of stilbenes resveratrol and oxyresveratrol on African swine fever virus replication Antiviral Research91: 57-63, 2011. CLAVE:A  IF: 4.439 PMID: 21557969

Hernáez B., T. Tarragó, E. Giralt, J. M. Escribano, and C Alonso.Small Peptide Inhibitors Disrupt a High-Affinity Interaction between Cytoplasmic Dynein and a Viral Cargo Protein. Journal of Virology 84 (20), 10792–10801, 2010.   CLAVE:A IF: 6.033 PMID: 20686048

Gil F., M. Perez-Filgueira, M. G. Barderas, C. Pastor-Vargas, C. Alonso, F. Vivanco and J. M. Escribano. Targeting antigens to an invariant epitope of the MHC Class II DR molecule potentiates the immune response to subunit vaccinesVirus Research 155: 55-60, 2010. CLAVE:A IF: 2.941PMID:21549789

Hernaez, B. and C. Alonso.Dynamin- and clathrin-dependent endocytosis in African swine fever virus entry.Journal of Virology 84(4):2100-9, 2010.CLAVE:A Impact factor 5.332 PMID: 19939916

Hernáez B., J M. Escribano and C. Alonso.The African swine fever virus protein p30 interacts with the heterogeneous ribonucleoprotein K (hnRNP-K) during infection FEBS Letters 582, 3275–3280, 2008. CLAVE:A IF: 3.601PMID: 18775702

Galindo I., B. Hernáez, G. Díaz-Gil, J.M. Escribano and C. Alonso. A179L, a viral Bcl-2 homologue, targets the core Bcl-2 apoptotic machinery and its upstream BH3 activators with selective binding restrictions for Bid and Noxa. VirologyVol 375(5): 561-572, 2008.IF: 3.525 PMID: 18329683

Carpintero R., C. Alonso, M. Piñeiro, M. Iturralde, M. Andrés, F. Madec, M. A. Álava, A. Piñeiro, F. Lampreave.Pig-Major Acute-Phase Protein and apolipoprotein A-I response correlated with the severity of experimentally induced African Swine Fever and Aujeszky´sdisease. Veterinary Research 38: 741–753, 2007. Indice de Impacto 2006 (IF): 3.152. PMID: 17637332

Rivera J., C. Abrahms, B. Hernaez, A. Alcázar, L. Dixon, J. M. Escribano and C Alonso.The MyD116-African Swine Fever viral homologue interacts with the catalytic subunit of protein phosphatase-1 and activates its phosphatase activity.Journal of Virology 81 (6): 2923- 2929, 2007. IF: 5.341. PMID: 17215279  

Alfonso P., J.I. Quetglás, J.M. Escribano and C. Alonso.Protein pE120R of African swine fever virus is post-translationally acetylated as revealed by post-source decay MALDI mass spectrometry.Virus Genes 35 (1): 81- 85, 2007. IF: 1.102 PMID: 16964554

X

X

Patentes

PATENTE RU2503686-C2 (WO/2009/053340) New antiviral composition comprises a peptide from African swine fever virus (ASFV) which prevents the binding of dynein light chain (DLC8), useful for treating infections attributable to a virus.Inventores: Covadonga Alonso, Jose M. Escribano, Bruno Hernáez.

PATENTE WO/2012/110636 Carrier peptides for cell delivery. Inventor/es: Covadonga Alonso and Jose Escribano

Endocitosis del virus de la peste porcina africana. https://vimeo.com/73620336

Special Issue African swine fever

Localization

Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA